3 D optimization Research Paper Example | Topics and Well Written Essays - 1500 words

3 D optimization - Research Paper Example Problems in 3-D dynamics are usually tackled using a combination of different fundamental approaches. These approaches include experimental fluid dynamics, theoretical fluid dynamics and computational fluid dynamics (CFD). CFD is what has opened the ‘three approach’ in the field of aerodynamics. CFD has had a big role to play in the analysis of aerodynamic configurations so as to aid the design process. The availability of high performance computing platforms have also aided in the development of aerodynamics (Reuther, Alonso & Jameson 1996). Both the mesh morpher algorithm and the direct search algorithm are gradient based optimization techniques. When using these designs in a 3D element optimization airfoil, the control function is parameterized with some set of design variables and a suitable cost function is either minimized or maximized. In order to show the dependence between the cost function and control function governing equations are introduced. The sensitivity derivatives of the cost function in retrospect to design variables are introduced in order to get a direction of improvement. The convergence to a minimum or maximum is achieved when the procedure is repeated. A fast and accurate way of calculating the necessary gradient information is imperative in developing a design that is effective and this is often the most time consuming part in the design algorithm. Therefore, this should be put into consideration when a very large number of design variables as in the case of the three dimensional wing shape desi gn are concerned. The plan of this research strategy is to produce 3D multi-element airfoil design and optimization mechanism that can adapt a model (3D airfoil) delivering enhanced aerodynamic performance in terms of maximizing lift to drag ratio under landing and takeoff flight situation (Reuther, Alonso & Jameson 1996). Processing the multi-element

Motivation of firms for foreign direct investments - a critical review Dissertation

Motivation of firms for foreign direct investments - a critical review - Dissertation Example The 1990s had witnessed a dramatic growth in the foreign direct investments to the developing countries. In the late 1980s, the net direct investment flows to the countries amounted from the 0.5 percent of their overall GDP to more than 2.5 percent in the year 2000-2001. The dramatic growth in FDI was particularly experienced in Latin America (Calderon, Loayza & Serven, â€Å"Introduction†). After 1994, with the steep decline in other private external flows, the significance of foreign direct investment has increased as the significant source of external financing to the developing world. Over the last few decades, the outsourcing from the foreign countries has become a significant strategic issue. This has been in the wake of increasing recognition of the benefits, provided by the effective outsourcing and international product strategies. In the quest for greater efficiency and cost savings, a number of companies have decided to source parts and components at a reduced cost from the suppliers across the globe. Hence, the importance of FDI has increased with the passing days. This report is an effort to look into the foreign direct investment from both the perspectives of domestic and foreign countries. There can be several benefits which can lead a host country to welcome the foreign direct investments while there are number motivations behind such decisions of the investing firms. All these have been discussed to have a more detailed look at the foreign direct investments taking reference from several articles and books, as well as the online resources. At the end, a conclusion has been inferred from the discussion carried out in different segments. Foreign Direct Investment Foreign Direct Investment is a form of investment which earns interest in the enterprises, functioning outside of the domestic territory of the investors. The foreign direct investment requires a business relationship between the parent company and its subsidiaries (EconomyWatch, â€Å"Types of Foreign Direct Investment: An Overview†). The term ‘Foreign Direct Investment’ can be defined in several ways. â€Å"Foreign Direct Investment (FDI) is the process whereby residents of one country (the source country) acquire ownership of assets for the purpose of controlling the production, distribution and other activities of a firm in another country (the host country)† (Moosa, p.1). According to International Monetary Fund’s Balance of Payments Manual, foreign direct investment is made to acquire an interest in any organisation, operating in a foreign economy; in this case, the investor aims to have to an effective voice in the organisation management. Back in the year 1999, the United Nations World Investment Report has defined FDI as an investment which involves a long term relationship and reflects a long-term interest and control of an entity in an organisation, in any foreign country. While compared to various forms of intern ational investment, the distinctive feature of FDI is that it enables the investor to have control over management policy and decisions of the organisation in the foreign country. A number of researchers have argued that the element of control has provided

Managing in a Strategic Business Context Essay Example | Topics and Well Written Essays - 4000 words

Managing in a Strategic Business Context - Essay Example An organization like HSBC Bank (especially Business Banking) believes that, if an organization follows like them the theories and concepts of the contemporary organizational context and the strategic management related to members, then it is not impossible to achieve the organizational goals accordingly. The aim of any SWOT analysis is to identify the key internal and external factors that are important to achieve the objective of an organization. SWOT analysis distinguishes key pieces of information into two main categories3: The internal factors may be identified as strengths or weaknesses depending upon their impact on the organization's objectives. What may represent strengths with respect to one objective may be weaknesses for another objective. The factors may include all of the 4P's 2 in accordance with personnel, finance, manufacturing capabilities, and so on. The external factors may influence macroeconomic matters, technological change, legislation, and socio-cultural changes, with the changes in the marketplace or competitive position. The results are usually represented in the form of a matrix. SWOT analysis is only method of categorisation and has its own weaknesses. For example, it may tend to persuade companies to compile lists rather than think about what is really important to achieve organizational goals. ... For example, it may tend to persuade companies to compile lists rather than think about what is really important to achieve organizational goals. It also represents the resulting lists simply and without clear prioritization so that, for example, weak opportunities may evolve to balance strong threats. Examples of Strengths and Weaknesses of HSBC Bank: Resources: Financial, intellectual and location are the strengths of the mentioned bank. Because HSBC Bank uses financial and intellectual resources to provide up to the mark services to the customers. Customer Service: As a service provider, customers are the main concern of HSBC Business Banking Sector. They believe that customers' satisfaction brings their success. They also assume this as their strength. Efficiency: Efficiency is the strength for the HSBC Bank as it ensures customers' satisfaction and organization's success. Quality: Quality is the strength for HSBC as they have good quality service. But in some cases they face it as weakness when they can't maintain the standard.Staff: In today's competitive market, inadequate number of staff is a weakness for HSBC. Management: HSBC Business Banking Sector works with Strategic Management, which helps them to work easily, and it is assumed as their strength that's why. Principles: HSBC Bank believes in good service providing to the customers in an effective and reasonable manner. This is the key component of their success. That's why they assume their principles as their strength of work. Examples of Opportunities and Threats of HSBC Bank3: Political/Legal: Political and legal unrest situations are often threats for the HSBC Business Banking Sector as it hampers their total management. Market Trends:

Motivation of firms for foreign direct investments - a critical review Dissertation

Motivation of firms for foreign direct investments - a critical review - Dissertation Example The 1990s had witnessed a dramatic growth in the foreign direct investments to the developing countries. In the late 1980s, the net direct investment flows to the countries amounted from the 0.5 percent of their overall GDP to more than 2.5 percent in the year 2000-2001. The dramatic growth in FDI was particularly experienced in Latin America (Calderon, Loayza & Serven, â€Å"Introduction†). After 1994, with the steep decline in other private external flows, the significance of foreign direct investment has increased as the significant source of external financing to the developing world. Over the last few decades, the outsourcing from the foreign countries has become a significant strategic issue. This has been in the wake of increasing recognition of the benefits, provided by the effective outsourcing and international product strategies. In the quest for greater efficiency and cost savings, a number of companies have decided to source parts and components at a reduced cost from the suppliers across the globe. Hence, the importance of FDI has increased with the passing days. This report is an effort to look into the foreign direct investment from both the perspectives of domestic and foreign countries. There can be several benefits which can lead a host country to welcome the foreign direct investments while there are number motivations behind such decisions of the investing firms. All these have been discussed to have a more detailed look at the foreign direct investments taking reference from several articles and books, as well as the online resources. At the end, a conclusion has been inferred from the discussion carried out in different segments. Foreign Direct Investment Foreign Direct Investment is a form of investment which earns interest in the enterprises, functioning outside of the domestic territory of the investors. The foreign direct investment requires a business relationship between the parent company and its subsidiaries (EconomyWatch, â€Å"Types of Foreign Direct Investment: An Overview†). The term ‘Foreign Direct Investment’ can be defined in several ways. â€Å"Foreign Direct Investment (FDI) is the process whereby residents of one country (the source country) acquire ownership of assets for the purpose of controlling the production, distribution and other activities of a firm in another country (the host country)† (Moosa, p.1). According to International Monetary Fund’s Balance of Payments Manual, foreign direct investment is made to acquire an interest in any organisation, operating in a foreign economy; in this case, the investor aims to have to an effective voice in the organisation management. Back in the year 1999, the United Nations World Investment Report has defined FDI as an investment which involves a long term relationship and reflects a long-term interest and control of an entity in an organisation, in any foreign country. While compared to various forms of intern ational investment, the distinctive feature of FDI is that it enables the investor to have control over management policy and decisions of the organisation in the foreign country. A number of researchers have argued that the element of control has provided

Compensation HR Essay Example | Topics and Well Written Essays - 750 words

Compensation HR - Essay Example This is mainly used to determine which job should get a higher pay than the other. There are methods used in job evaluation such as job grading, job ranking and factor comparison. Job evaluation is advantageous as it helps to define a job according to an individual specialization so as to fix the fairest salary on it. Job evaluation analysis also helps when selecting a job that relates to the qualifications of an employee. Jobs are evaluated by ranking jobs. This is by evaluating a job using a single factor such as how technical a job is, or the educational level requires needed to perform the job effectively. The more technical a job and the higher the educational level required, the higher the job is ranked. Compensation is then based on the ranking where the highest in the rank is paid more (Poels and Frans 22). Salary surveys are normally used in job evaluation. This is by comparing a job with the same kind of job, with the same description and the same expectations in another organization in the job market. This helps in knowing how competitive the organization is as compared to other organizations. As a result of this survey, the ranges of salaries are normally revised as soon as the survey shows the need of a revision. This helps the organization stay competitive in the market. Compensation program is important in attracting and retaining talented employees. The program is normally done by the human resource manager. This is normally done together with the training and development officer. The aim of a training and development officer is to ascertain the performance of employees. This is so as to see if they have reached the set target of if they have improved in their performance. This helps the human resource manager department in efficiently administering the compensation program. Merit increase is given based on the performance of an employee where, if an employee performs better, they get a better compensation. There is

Hybrid Cars Essay Example for Free

Hybrid Cars Essay Company: Within the company there are a few areas to look at regarding Toyotas introduction of the Prius. Areas such as financing, research, development, as well as others. When introducing the Prius, Toyota started early with its promotion of the hybrid. Spending US$15 million out of the US$190 million is spent on marketing in the 2002 year. Toyota informed its potential customers threw informative emails, TV commercials, and earth day give a ways. Toyota put a lot into research and development to come up with the hybrid with the advances in technology, such as the engine of the Prius. The engine combines a 1. 5 litre, 4 cylinder gas engine, with a 33-kilowatt electric engine that runs of a nickel-hydride battery. With this new engine and normal highway driving conditions the car is said to get 106 km per gallon. It is also rated one of the greenest vehicles on the market. Since North Americans complain about gas mileage, and want to be environmentally friendly this seems like the way to go. Suppliers: One of Toyotas major costs of manufacturing the Prius would be the nickel-hydride battery that the electric part fo the engine runs off of. This is also one of the main reasons why hybrid cars are so expensive compared to similar gas powered cars of the same size. But if manufacturers of hybrid cars were to see a yield in economies of scale then there would be more reason for producers of the battery to put more time and money into research and development of the battery and thus decrease costs of producing it. this would in term pass savings onto the potential buyers of the hybrid car. Customer Market: when looking for a way to market the Prius to consumers Toyota looked at what consumers wanted in a vehicle. Things like lower gas mileage, lower emmissions, and something that what technologically appealing. so with this in mind Toyota set out to design a car to appeal to all these things. with the combined electric and gas engine the Prius gets better mileage, and one of the greenest vehicles on the market. consumers have also been able to technologically modify there Prius, some have added DVD players and such, or programmed the cars computer to shower videos etc, on the monitors in the car. Competitors: introducing the Prius was the way in which Toyota planned to get an advantage over competitors like the big three auto manufacturers (ford, GM, DaimlerChrysler) none of whom had a hybrid in market when the Prius was released. the big three had plans of releasing hybrid vehicles in 2003, Toyota planned to stay on top of the hybrid market with its early release of a hybrid. Publics: there are a lot of different publics to take in mind. publics such as the media, government, citizen-action, local, general, etc. Toyota used a lot of these when it can to promoting the Prius. they ran articles, in vanity air, and newsweek, as well as running commercials on different television statements such as discovery, the history channel, and the learning network. it ran different taglines, such as A car that sometimes runs on gas power and sometimes runs on electric power, from a company that always runs on brain power. it also used tag lines that drew the customer in to find the meaning in it and also educating the customer on what exactly a hybrid was. Question # 2: Demographic Forces: this is one of the key forces that affect marketing plans it involves the study of people and when they want. Toyota looked at the different things that people wanted in a car. things like low fuel usage, and being environmentally friendly. using the information gathered Toyota came up with the combined engine that runs on gas and electric power to reduce mileage and also make it environmentally friendly. this hybrid would more likely be targeted to generation Y drivers. seeing as they are younger and more into the technological advances in society. it would also be marketed to the generation X drivers for the fact that they are more concerned over the outlook of the environment. Natural Forces: with natural forces marketers would be aware of trends, like the shortage or raw materials trend, the increase of population, and the government. with the government putting more emphasis on being environmentally friendly Toyota seems to have taken this to heart seeing as the Prius is one of the greenest vehicles on the market. also with the population tending to gather around more urban settings it is becoming more essential to have a vehicle with better gas mileage with more people commuting back and forth to work. Technological Forces: with the advances in technology recently people now except more from manufactures. Toyota seeing this used it to its advantage using the combined engine and adding other features as a computer system installed right in the car. it also used the internet as one of the ways it go to potential consumers to educate them on the Prius and what it was all about. which in turned created sales of the hybrid. Political: on problem with the Prius is that its not all that affordable. so makers of hybrid cars have gone to the government to see if there was a way to incorporate a benefit of driving a environmentally friendly car. while the US now offers a tax benefit for driving such a car there has yet to be any incentive in Canada. since there is no documented proof as of yet that driving one of these cars helps the environment they do not see the point in implicating anything yet. Cultural: the cultural force takes into account the values and beliefs of the consumer.like being friendly to the environment. valuing technology, etc. Toyota conformed to these by using the combined engine, not only is it environmentally friendly is also increased gas mileage. it also put a lot of new technologies into the Prius that consumers are finding many ways to use to their advantage. doing things like tweaking the computer system to play videos and mp3s, etc. Question # 3: Value proposition is essentially the full mix of benefits upon which the brand is positioned. Toyota sets the benefits to come from the higher gas mileage, the fact that it lowers emmissionsÃ'Ž

An Overview of Butadiene

An Overview of Butadiene 1,3 Butadiene 1,3-Butadiene with its molecular structure of [emailprotected]=CH2 have widely synonym as butadiene,,-butadiene, divinyl, buta-1,3-diene, vinylethylene, vinylethylene, bivinyl, erythrene, biethylene, and pyrrolylene refer to the same physical and chemical properties. It has same Chemical Abstracts Service (CAS) registry number which is 106-99-0, and its Registry of Toxic Effects of Chemical Substances (RTECS) number is EI9275000. As compared to the air, the conversation factor of to 1ppm butadiene is equal to 2.21 mg/m3 in the air. Further important identity and physicochemical properties of butadiene is described as per Table 1. Â   Generally, butadiene was produce during combustion resulting from combustion of organic matters whether it come from natural process or human activities. Among of natural process and human activities, the main contributor of butadiene presence in earth majorly come from human activity which cause high impact to surrounding life and environment. As part of human activities, 1,3 Butadiene being used primarily and commercially in the making of synthetic rubbers and polymers. 1,3 butadiene was produced by complex and specific process as co-product of ethylene during cracking at high temperature (produced C4) at the steam crackers units. The crude C4 that produced from steam cracker units or process then fed to the butadiene extraction units for separation process of butadiene, isobutenes and the other C4s (byproduct called as Raffinate 1) through extractive distillation. The most advanced Butadiene extraction technology is come from BASF NMP Process in which 1,3 Butadiene is extract as per Diagram 1 by utilized N-methyl-2-pyrrolidone (NMP) as solvent. Characteristic 1,3-Butadiene is colourless gas at room temperature with gasoline or mild aromatic odor, highly flammable when exposed to heat and insoluble in water but soluble in ether, acetone, benzene and ethanol. It is very reactive: it may form acrolein and peroxides upon exposure to air, it can react with oxidizing materials, and it polymerizes readily, particularly if oxygen is present. Butadiene is stabilized with hydroquinone, catechol, t-butyl catechol or aliphatic mercaptans1,2. In addition from that, as per GHS-US classification, 1,3 Butadiene is classified and hazard label as per Table 2 and Diagram 2 below: CLASS Hazard Statement Description H220 Flammable Gas Category 1 Exteremly flammable gas H280 Refrigerated Liquefied Gas Contains gas under pressure; may explode if heated H315 Skin Irritation Category 2 Causes skin irritation H319 Eye Irrititation Category 2A Causes serious eye irritation H340 Germ Cell Mutagen Category 1B May cause genetic defects H350 Carcinogen Category 1A May cause cancer Table 2: Classification of 1,3 Butadiene as per GHS-US Classficiation Diagram 2: Hazard label/pictogramns of 1,3 Butadiene as per GHS-US Classficiation Used 1,3 Butadiene is the main raw material to manufacture variety type of rubbers and plastics. It is being used as an intermediate ingredient; monomers in production of polymers, synthetic rubbers or elastomers, and other chemicals. As substitution for natural rubber, Butadiene being used widely in producing synthetic rubbers and polymer which offers numerous advantages in term of improvement in performance, safety and functionality, and lower costs. Over 75% of 1,3 Butadiende was used to produce Synthetic rubber. Synthetic rubber derived from 1,3 butadiene include Styrene-butadiene rubber (SBR), poly-butadiene rubber (PBR), nitrile rubber (NR) and poly-chloroprene(Neoprene). These synthetic rubbers then undergo several others specific process to produce product like: Styrene-butadiene rubber (SBR) and poly-butadiene rubber (PBR) are used in the making of tyres and plastic where able to enhance and increase the resistance of vehicles tyre and plastic towards heat degradation, blowouts, wear and tear. Neoprene or poly-chloroprene is used extensively in manufacture of latex goods which is non-tire application such as gloves, foams, waders and wearsuits. Nitrile Rubber(NR) have variety of end product which mainly used to produce rubber hoses, gasket and seals for automobiles . Remaining 25% of 1,3 Butadiene was used to produce polymers. Polymerd derived from 1,3 include Acrylonitrile-butadiene-styrene (ABS) resins, poly-butadiene polymers, nitrile barrier resins and thermoplastic resins. Among the others, ABS resin was widely used in large volume of thermoplastic resin, containing about 20%- 30% of 1,3 butadiene by weight to produce automobiles part and appliances in automotive industry . Apart from that, 1,3- Butadiene also is used in the production of adhesives for packaging, transporting, or holding food; in components of paper and paperboard that are in contact with dry food; and as a modifier in the production of semirigid and rigid vinyl chloride plastic food-contact articles. Human Exposure The general human exposure can be separated onto two: occupational exposure and non-occupational exposure and describe as per below: 1.3.1 Occupational exposure The highest exposure of butadiene is mainly occurs in occupational settings or workplace area and its surroundings. Potential areas include several industries like: petroleum refinery and operation plant (where the crude C4 cracking process take over and involves butadiene extraction, gasoline production and distribution), distillation and production of butadiene monomer plant, factory or manufacturer of various butadiene based product like synthetic rubber and polymers plant such as tires, gloves and variety injection moulding industries (IARC, 1999). Based from data collected from European Chemical Bereau during 1984 to 1987, the arithmetic means of butadiene concentration at petrochemical and petroleum refinery plant industries area in several location of European countries is ranged from 0.1 to 6.4 mg/m3 Other than that, by refer from survey conducted by occupational hygiene of United Kingdom shows that the mean concentration of butadiene generally below 11mg/m3 with most below 2.2 mg/m3 for butadient production areas while in polymer manufacturer area time-weighted averaged around (4.4 to 6.6mg/m3). Meanwhile at USA in 1985, the arithmetic mean concentration is ranged from 1 to 277 mg/m3 for monomer production plant and 0.04 to 32mg/m3 for polymer production plant. (IARC, 1999; European Chemicals Bureau, 2001). 1.3.2 Non-occupational exposure For non-occupational exposure area, it is obtained that the butadiene mean concentration in ambient air is much lower in ÃŽÂ ¼g/m3 measured than reported in occupational exposure area which measured in mg/m3. Elevation of concentration observed occurs at the vicinity of source like municipal structural fires area, smoking shed or cigarette smoke area, brush and wood fires Butadiene has been widely detected in ambient air but at much lower levels (ÃŽÂ ¼g/m3) than reported in some occupational settings (mg/m3). Elevated concentrations may occur in the vicinity of point sources, such as municipal structural fires, wood and brush fires; cigarette smoking; volatilization gasoline area as well as combustion through vehicle emissions (IARC, 2008). Based on data and study conducted during 1990 and 1994, involvement of 14 cities, rural or towns at Ontario, Canada shows that the results from 1611 samples of outdoor air collected for mean concentration of butadiene is ranged around 0.1ÃŽÂ ¼g/m3 with maximum of 1.7 ÃŽÂ ¼g/m3. (Health Canada, 2000). Dollard et al. (2007) measured butadiene concentrations at rural, urban background (UB), urban industry influenced (UI) and busy-roadtraffic (BR) locations in the United Kingdom from 1993 to 2004. Mean rural levels dropped from 0.39 to 0.02 ÃŽÂ ¼g/m3 between 1995 and 2004; mean UB levels decreased from 0.64 to 0.15 ÃŽÂ ¼g/m3 in 1993-2004; mean UI levels came down from 0.85 to 0.35 ÃŽÂ ¼g/m3 in 1995-2000; and mean BR levels went from 3.3 to 0.57 ÃŽÂ ¼g/m3 in the period 1997-2004. . Human effect Exposure of 1,3 Butadiene can effect human health and the severity can be separated into two, which is acute and chronic. For acute exposure, it can be further split into high doses and low doses. Acute low doses exposure will caused irritation to nose, eyes, lungs and throat. These frostbite injury also may lead to occur through exposure to skin. Acute high doses of exposures will lead to cause damage of central nervous system by showing symptoms to human body such vertigo, general tiredness, distorted blurred vision headache, nausea fainting and decrease pulse rate. Human epidemiological studies has been conducted to identify the Chronic effects to human that cause by exposure to 1,3-butadiene, the result shown the effect to human can cause cancer and cardiovascular diseases. However, due to some limitation and cofounding factors in study of cancer to human due to exposure by 1,3-Butadiene such as simultaneous exposure to syrene and benzene, smoking; the exact causal factors unable to established well. Extensive lab experiment involving animal such as mice and rat has been performed and study to observe relationship of chronic exposure of 1,3-butadiene to cancer. The studies through mice and rat has shown the developmental problems and reproductive effected the animals. Through this study, 1,3-Butadiene has been classified as human carcinogen from EPA and rated as A2; suspected human carcinogen as per The American Conference of Governmental Industrial Hygienists (ACGIH). Further human effect exposed to 1,3-butadiene explain on Table 2. Carcinogenicity to human Based on epidemiological studies conducted shows that high tendancy or risk of leukemia or others cancer to attacked on the lymphohaematopoietic system when chronic exposure to 1,3-Butadiene. This involve three studies on employed workers at 1,3-Butadiene production facility of styrene-butadiene-rubber(SBR) plant where the major exposure is 1,3-butadiene monomer alone. The result of the studies shows the same relation or overlapping cohort population. It was observed in two studies at butadiene monomer facility, overall have slightly excess of mortality from leukaemia while in third study shows decrease in mortality of leukaemia. The increased mortality from leukaemia in one of the monomer industry cohorts was more pronounced among workers who had been exposed at high levels during the first years of production (Second World War). In this cohort, no increase in leukaemia was observed with duration of exposure or cumulative exposure. Based on the study on SBR workers by University of Alabama at Birmingham (USA) considered as very informative data where the study involves in examine the mortality rates of about 17,000 workers through eight facility in Canada and USA. A limiting factor in the evaluations was that the diagnosis and classification of lymphatic and haematopoietic malignancies are very complex and have undergone several changes over the course of time. Although overall mortality from leukemia was only slightly higher in the update of the most recent cohort, a larger increase of deaths from leukemia seen in workers in the most highly exposed from plants and one employee per hour paid, especially those who was hired in early years and has ten years or more jobs. Furthermore, a significant correlation between cumulative exposure of 1,3-butadiene and leukemia deaths observed in this study. A recent analysis shows that the exposure-response relationship for 1,3-butadiene and leukemia are free from exposure to styrene and dimethyldithiocarbamate. Studies with mice showed increased tumour formation in various organs in both sexes at 1,3-butadiene exposures to approximately 14 mg/m3 (females) and 44 mg/m3 (males). This was not observed in rats at exposures up to 2,200 mg/m3, likely due to the crucial role of oxidative metabolism: 1,3-butadiene requires metabolic activation to generate electrophilic epoxides in which important species differences exist (mice are more efficient in the production of epoxide metabolites of butadiene, while rats and humans are more efficient in the hydrolytic detoxification of these metabolites). Many tests on mutagenicity, genotoxicity and mechanism of action clearly indicate that 1,3-butadiene is a genotoxic compound in humans and in experimental animals, requiring metabolic activation to generate electrophilic and DNA-reactive epoxides (epoxybutene, epoxybutanediol and diepoxybutane), one or more of which are considered to be the ultimate carcinogens. Health Effect Description Symptoms Inhalation problem or respiratory irritation Inhalation of 1,3 butadiene gases or aerosols such as mists or fumes generated by the material during handling and normal works can be damaging the human health. Excessive exposures can cause severe irritation to upper respiratory system or central nervous system like nose and throat. 1, 3 butadiene can cause narcotic effects or anesthetic including dizziness and drowsiness, alertness, sleepiness, lack of coordination, vertigo, loss of reflexes and death. Ingestion Drink or food that contaminate with 1,3-Butadiene which the residues of 1,3-butadiene have been found in drink and food container. (McNeal and Breder 1987) Liquid butadiene can cause frostbite to the lips but this unlikely to happen because very low amount of butadiene used in food and drink containers. Eye Person or human can be exposed to the 1,3 Butadiene liquid and gases during manufacture or at occupational area Transient discomfort characterised by tearing or conjunctival redness, pain and blurred vision.exposed to liquid butadiene can cause frostbite if it contacts the eyes and rapidly evaporates. Skin Contact Not to have any skin irritation or harmful to human health in normal condition. It will affected if the person involve in injury or wound In touch with liquid butadiene may cause frostbite and rapidly evaporate. When entry into the blood-stream, through cuts, abrasions or lesions, may produce systemic injury with harmful effects. Chronic As per International Agency for Research on Cancer (IARC), Butadiene is listed as human carcinogen which can directly cause cancer in human. Based on experiments, there is an evident that butadiene can cause genetic defect and may result in toxic effecs to the unborn baby. Cancer ex: leukemia, damaged of cardiovascular system, genetic defect Table 2: Health effect of 1,3 Butadiene to human health Reduce the risk of hazardous In order to reduce risk of hazardous of 1,3butadiene, many precaution and controls shall take in consideration. Separated into two; occupational and non-occupational exposure. 4.1 Occupational The higher human exposure to 1,3 Butadiene is come from occupational environment. Appropriate control can be taking in consideration to reduce the risk exposure by include appropriate engineering controls, hand protection, eye protection, skin and body protection, respiratory protection and environmental exposure control. 4.1.1 A Appropriate engineering controls Appropriate engineering controls : This product must be confined with vapor-tight equipment. With this confinement, vapors should not be released, and local exhaust should be satisfactory. An explosion-proof system is acceptable. Ensure that any venting of material is in compliance with international, federal/national, state/provincial, and local regulations. Hand protection : Wear protective gloves made of PVC. Eye protection : Wear safety glasses with side shields. Wear safety glasses with side shields or goggles when transfilling or breaking transfer connections. Provide readily accessible eye wash stations and safety showers. Skin and body protection : Wear work gloves and metatarsal shoes for cylinder handling. Protective equipment where needed. Select in accordance with OSHA 29 CFR 1910.132, 1910.136, and 1910.138. Respiratory protection : When workplace conditions warrant respirator use, follow a respiratory protection program that meets OSHA 29 CFR 1910.134, ANSI Z88.2, or MSHA 30 CFR 72.710 (where applicable). Use an air-supplied or air-purifying cartridge if the action level is exceeded. Ensure that the respirator has the appropriate protection factor for the exposure level. If cartridge type respirators are used, the cartridge must be appropriate for the chemical exposure. For emergencies or instances with unknown exposure levels, use a self-contained breathing apparatus (SCBA). Environmental exposure controls : Refer to local regulations for restriction of emissions to the atmosphere. See section 13 for specific methods for waste gas treatment. Refer to local regulations for restriction of emissions to the atmosphere. Other information : Consider the use of flame resistant anti-static safety clothing. Wear safety shoes while handling containers. Keep suitable chemically resistant protective clothing readily available for emergency use. Wear leather safety gloves and safety shoes when handling cylinders. Non-occupational Wood burning Take precautions to minimize the amount of smoke released into the home during wood burning. Vehicle engines Make sure vehicle engines are turned off when in an enclosed space such as a garage. Vehicle traffic Minimize time spent near areas of heavy vehicle traffic and avoid living very close to busy roads. Tobacco smoke Families can reduce exposure to 1,3-butadiene by avoiding tobacco smoke, particularly indoors.